We reported that GABA concentration in the brain motor areas was linked to the level of motor disabilities of ASD individuals. We applied MRspectroscopy for measuring GABA concentration in human brain and BOT-2 for assessing the level of motor skills. Interestingly, the primary motor area (M1) and supplementary motor area (SMA) were differenctly correlated with performances of the gross movements and coordinated movements, respectively.

 

Authors: Umesawa Y*, Matsushima K, Atsumi T, Kato T, Fukatsu R, Wada M, Ide M*

*Corresponding authors

Title: Altered GABA concentration in brain motor area is associated with the severity of motor disabilities in individuals with autism spectrum disorder

Journal: Journal of Autism and Developmental Disorders

Journal site: https://link.springer.com/article/10.1007/s10803-020-04382-x